› 5i2o

X-ray diffraction
1.95Å resolution

Structure of EF-hand containing protein

Released:
DOI: 10.2210/pdb5i2o/pdb
PDB entry 5i2o coloured by chain, front view.
PDB entry 5i2o coloured by chain, side view.
PDB entry 5i2o coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural implications of Ca2+-dependent actin-bundling function of human EFhd2/Swiprosin-1.
Park KR, Kwon MS, An JY, Lee JG, Youn HS, Lee Y, Kang JY, Kim TG, Lim JJ, Park JS, Lee SH, Song WK, Cheong HK, Jun CD, Eom SH
Sci Rep 6 39095 (2016)
PMID: 27974828

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188394 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
EF-hand domain-containing protein D2 Chain: A
Molecule details ›
Chain: A
Length: 120 amino acids
Theoretical weight: 13.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96C19 (Residues: 70-184; Coverage: 48%)
Gene names: EFHD2, SWS1
Sequence domains: Allograft inflammatory factor 1
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P212121
Unit cell:
a: 36.254Å b: 51.529Å c: 53.567Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.184 0.204
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Getting cells into shape by calcium-dependent actin cross-linking proteins.
Lehne et al. (2023)
11 other articles

1 mention without citation

Structural implications of Ca2+-dependent actin-bundling function of human EFhd2/Swiprosin-1.
Park et al. (2016)