› 5i2m

X-ray diffraction
2.4Å resolution

CRYSTAL STRUCTURE OF VSV-INDIANA (MUDD-SUMMERS STRAIN) GLYCOPROTEIN UNDER ITS ACIDIC CONFORMATION

Released:
DOI: 10.2210/pdb5i2m/pdb
PDB 5i2m coloured by chain and viewed from the front.
PDB 5i2m coloured by chain and viewed from the side.
PDB 5i2m coloured by chain and viewed from the top.
Source organism: Vesicular stomatitis Indiana virus strain Mudd-Summers
Primary publication:
Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G.
Roche S, Bressanelli S, Rey FA, Gaudin Y
Science 313 187-91 (2006)
PMID: 16840692

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycoprotein G Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 422 amino acids
Theoretical weight: 47.34 KDa
Source organism: Vesicular stomatitis Indiana virus strain Mudd-Summers
UniProt:
  • Canonical: P0C2X0 (Residues: 1-422; Coverage: 100%)
Gene name: G
Sequence domains: Rhabdovirus spike glycoprotein
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand PE4 5 x PE4
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: C2221
Unit cell:
a: 71.27Å b: 224.2Å c: 375.74Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.183 0.215

Quick links

Citations

66 review citations

Emerging Biomedical Applications of the Vesicular Stomatitis Virus Glycoprotein.
Rehman et al. (2022)
65 more

7 mentions without citation

Monomeric Intermediates Formed by Vesiculovirus Glycoprotein during Its Low-pH-induced Structural Transition.
Abou-Hamdan et al. (2018)
6 more