› 5i0n

X-ray diffraction
2.28Å resolution

PI4K IIalpha bound to calcium

Released:
DOI: 10.2210/pdb5i0n/pdb
PDB 5i0n coloured by chain and viewed from the front.
PDB 5i0n coloured by chain and viewed from the side.
PDB 5i0n coloured by chain and viewed from the top.
Source organisms:
Entry authors: Baumlova A, Boura E

Function and Biology Details

Reaction catalysed: 
ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endolysin; Phosphatidylinositol 4-kinase type 2-alpha Chain: A
Molecule details ›
Chain: A
Length: 556 amino acids
Theoretical weight: 63.24 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: D9IEF7 (Residues: 2-164; Coverage: 99%)
  • Canonical: Q9BTU6 (Residues: 76-172, 180-468; Coverage: 81%)
Gene names: PI4K2A, T4Tp126, e
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand ATP 2 x ATP
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P21212
Unit cell:
a: 78.882Å b: 102.028Å c: 78.929Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.219 0.258
Expression system: Escherichia coli

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