X-ray diffraction
2.28Å resolution

PI4K IIalpha bound to calcium

Source organisms:
Entry authors: Baumlova A, Boura E

Function and Biology Details

Reaction catalysed:
ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Endolysin; Phosphatidylinositol 4-kinase type 2-alpha Chain: A
Molecule details ›
Chain: A
Length: 556 amino acids
Theoretical weight: 63.24 KDa
Source organisms: Expression system: Escherichia coli
  • Canonical: D9IEF7 (Residues: 2-164; Coverage: 99%)
  • Canonical: Q9BTU6 (Residues: 76-172, 180-468; Coverage: 81%)
Gene names: PI4K2A, T4Tp126, e
Sequence domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P21212
Unit cell:
a: 78.882Å b: 102.028Å c: 78.929Å
α: 90° β: 90° γ: 90°
R R work R free
0.221 0.219 0.258
Expression system: Escherichia coli