X-ray diffraction
2.42Å resolution

Crystal structure of the orphan region of human endoglin/CD105


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Endoglin; Maltose/maltodextrin-binding periplasmic protein Chain: A
Molecule details ›
Chain: A
Length: 692 amino acids
Theoretical weight: 75.25 KDa
Source organisms: Expression system: Homo sapiens
  • Canonical: P0AEX9 (Residues: 27-393; Coverage: 99%)
  • Canonical: P17813 (Residues: 26-337; Coverage: 49%)
Gene names: END, ENG, JW3994, b4034, malE
Sequence domains: Bacterial extracellular solute-binding protein

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P65
Unit cell:
a: 114.15Å b: 114.15Å c: 120.62Å
α: 90° β: 90° γ: 120°
R R work R free
0.222 0.22 0.263
Expression system: Homo sapiens