X-ray diffraction
1.8Å resolution

Crystal structure of DR2231_E46A mutant in complex with dUMP and magnesium


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
HAD superfamily Cof-like phosphohydrolase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 138 amino acids
Theoretical weight: 14.97 KDa
Source organism: Deinococcus radiodurans
Expression system: Escherichia coli BL21
  • Canonical: Q9RS96 (Residues: 7-144; Coverage: 93%)
Gene name: DR_2231
Sequence domains: Phosphoribosyl-ATP pyrophosphohydrolase
Structure domains: putative ntp pyrophosphohydrolase like domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21212
Unit cell:
a: 148.827Å b: 77.813Å c: 52.266Å
α: 90° β: 90° γ: 90°
R R work R free
0.175 0.173 0.213
Expression system: Escherichia coli BL21