› 5hsf

X-ray diffraction
1.52Å resolution

1.52 Angstrom Crystal Structure of Fc fragment of Human IgG1.

Released:
DOI: 10.2210/pdb5hsf/pdb
PDB entry 5hsf coloured by chain, front view.
PDB entry 5hsf coloured by chain, side view.
PDB entry 5hsf coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Minasov G, Halavaty A, Shuvalova L, Dubrovska I, Winsor J, Flores K, Bishop B, Kwon K, Anderson WF, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134849 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Immunoglobulin heavy constant gamma 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 132 amino acids
Theoretical weight: 15.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P01857 (Residues: 221-343; Coverage: 28%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand PGE 2 x PGE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P21
Unit cell:
a: 47.713Å b: 43.88Å c: 49.579Å
α: 90° β: 92.64° γ: 90°
R-values:
R R work R free
0.159 0.157 0.188
Expression system: Escherichia coli BL21(DE3)

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