PDBe 5hpd

Solution NMR

Solution Structure of TAZ2-p53TAD

Released:

Function and Biology Details

Reaction catalysed:
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CREB-binding protein; Cellular tumor antigen p53 Chain: A
Molecule details ›
Chain: A
Length: 158 amino acids
Theoretical weight: 17.71 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04637 (Residues: 2-61; Coverage: 15%)
  • Canonical: P45481 (Residues: 1764-1855; Coverage: 4%)
Gene names: Cbp, Crebbp, P53, TP53
Sequence domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: simulated annealing, molecular dynamics
Chemical shifts: BMR30004  
Expression system: Escherichia coli BL21(DE3)