PDBe 5hob

X-ray diffraction
1.22Å resolution

p73 homo-tetramerization domain mutant I

Released:
Source organism: Homo sapiens
Entry authors: Coutandin D, Krojer T, Salah E, Mathea S, Knapp S, Dotsch V

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor protein p73 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 50 amino acids
Theoretical weight: 6.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O15350 (Residues: 351-398; Coverage: 8%)
Gene names: P73, TP73
Structure domains: p53-like tetramerisation domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P1
Unit cell:
a: 29.05Å b: 48.4Å c: 75.73Å
α: 89.6° β: 83.2° γ: 74.27°
R-values:
R R work R free
0.19 0.188 0.214
Expression system: Escherichia coli