› 5hmc

X-ray diffraction
2.2Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioesterase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 15.42 KDa
Source organism: Streptomyces sahachiroi
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: B4XYA6 (Residues: 1-133; Coverage: 100%)
Gene name: azi13
Sequence domains: Thioesterase superfamily
Structure domains: Hotdog Thioesterase

Ligands and Environments

2 bound ligands:
Ligand 5NE 1 x 5NE
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: I4122
Unit cell:
a: 67.771Å b: 67.771Å c: 140.278Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.184 0.219
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 citations in other articles

Thioesterase enzyme families: Functions, structures, and mechanisms.
Caswell et al. (2022)

427 mentions without citation

Circulating Tumor DNA-A Novel Biomarker of Tumor Progression and Its Favorable Detection Techniques.
Wen et al. (2022)
426 more