PDBe 5hm3

X-ray diffraction
2.25Å resolution

2.25 Angstrom Resolution Crystal Structure of Long-chain-fatty-acid-AMP Ligase FadD32 from Mycobacterium tuberculosis in complex with Inhibitor 5'-O-[(11-phenoxyundecanoyl)sulfamoyl]adenosine

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Long-chain-fatty-acid--AMP ligase FadD32 Chain: A
Molecule details ›
Chain: A
Length: 657 amino acids
Theoretical weight: 71.89 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Best match: O53580 (Residues: 2-637)
Gene names: Rv3801c, fadD32

Ligands and Environments


2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P212121
Unit cell:
a: 62.779Å b: 74.558Å c: 127.762Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.185 0.239
Expression system: Escherichia coli BL21(DE3)