X-ray diffraction
2.76Å resolution

Function and Biology Details

Reaction catalysed:
ATP + D-hexose = ADP + D-hexose 6-phosphate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Hexokinase-2 Chain: A
Molecule details ›
Chain: A
Length: 922 amino acids
Theoretical weight: 102.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P52789 (Residues: 17-916; Coverage: 98%)
Gene name: HK2
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P3121
Unit cell:
a: 165.12Å b: 165.12Å c: 126.478Å
α: 90° β: 90° γ: 120°
R R work R free
0.22 0.218 0.266
Expression system: Escherichia coli