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The third PDZ domain from the synaptic protein PSD-95 (H372A mutant)

X-ray diffraction
1.75Å resolution
PDB entry 5hf4 coloured by chain, front view.
PDB entry 5hf4 coloured by chain, side view.
PDB entry 5hf4 coloured by chain, top view.
Source organism: Rattus norvegicus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Disks large homolog 4
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Multimeric state: monomeric
Accessible surface area: 6874.43 Å2
Buried surface area: 251.43 Å2
Dissociation area: 125.72 Å2
Dissociation energy (ΔGdiss): 0.28 kcal/mol
Dissociation entropy (TΔSdiss): 1.14 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-151877

Macromolecules

Disks large homolog 4
Chain: A
Length: 119 amino acids
Theoretical weight: 12.67 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P31016 (Residues: 302-402; Coverage: 14%)
Gene names: Dlg4, Dlgh4, Psd95
Pfam: PDZ domain
InterPro:
CATH: Pdz3 Domain
Disks large homolog 4 in PDB entry 5hf4, assembly 1, front view.
Disks large homolog 4 in PDB entry 5hf4, assembly 1, side view.
Disks large homolog 4 in PDB entry 5hf4, assembly 1, top view.
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