X-ray diffraction
3.82Å resolution

Structure of full-length extracellular domain of HAI-1 at pH 4.6


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Kunitz-type protease inhibitor 1 Chain: A
Molecule details ›
Chain: A
Length: 421 amino acids
Theoretical weight: 47.3 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
  • Canonical: O43278 (Residues: 36-457; Coverage: 82%)
  • Best match: O43278-2 (Residues: 36-441)
Gene names: HAI1, SPINT1, UNQ223/PRO256
Sequence domains:
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P41212
Unit cell:
a: 95.62Å b: 95.62Å c: 124.58Å
α: 90° β: 90° γ: 90°
R R work R free
0.256 0.253 0.328
Expression system: Drosophila melanogaster