› 5h0j

X-ray diffraction
1.8Å resolution

The crystal structure of WT Pedobacter heparinus SMUG2

Released:
DOI: 10.2210/pdb5h0j/pdb
PDB entry 5h0j coloured by chain, front view.
PDB entry 5h0j coloured by chain, side view.
PDB entry 5h0j coloured by chain, top view.
Source organism: Pedobacter heparinus DSM 2366
Primary publication:
SMUG2 DNA glycosylase from Pedobacter heparinus as a new subfamily of the UDG superfamily.
Pang P, Yang Y, Li J, Wang Z, Cao W, Xie W
Biochem J 474 923-938 (2017)
PMID: 28049757

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111658 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uracil-DNA glycosylase-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 244 amino acids
Theoretical weight: 28.21 KDa
Source organism: Pedobacter heparinus DSM 2366
Expression system: Escherichia coli
UniProt:
  • Canonical: C6Y1J8 (Residues: 1-236; Coverage: 100%)
Gene name: Phep_0752
Sequence domains: Uracil DNA glycosylase superfamily

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P41212
Unit cell:
a: 56.506Å b: 56.506Å c: 144.242Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.18 0.197
Expression system: Escherichia coli

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Citations

1 review citation

Evolutionary Origins of DNA Repair Pathways: Role of Oxygen Catastrophe in the Emergence of DNA Glycosylases.
Prorok et al. (2021)
4 other articles