5gzr

Electron Microscopy
9.4Å resolution

Zika virus E protein complexed with a neutralizing antibody Z23-Fab

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero 600-mer (preferred)
hetero decamer
hetero 50-mer
hetero 60-mer
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
structural protein E Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 504 amino acids
Theoretical weight: 54.44 KDa
Source organism: Zika virus
UniProt:
  • Canonical: A0A1B0XTC8 (Residues: 291-794; Coverage: 15%)
Sequence domains:
strutural protein M Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 75 amino acids
Theoretical weight: 8.5 KDa
Source organism: Zika virus
UniProt:
  • Canonical: A0A1B0XTC8 (Residues: 216-290; Coverage: 2%)
Sequence domains: Flavivirus envelope glycoprotein M
Z23 Fab heavy chain Chains: H, M
Molecule details ›
Chains: H, M
Length: 221 amino acids
Theoretical weight: 23.52 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Z23 Fab light chain Chains: L, N
Molecule details ›
Chains: L, N
Length: 214 amino acids
Theoretical weight: 23.42 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 9.4Å
Relevant EMDB volumes: EMD-9542
Expression system: Homo sapiens