PDBe 5gzo

X-ray diffraction
2.76Å resolution

Structure of neutralizing antibody bound to Zika envelope protein

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Genome polyprotein Chains: A, B
Molecule details ›
Chains: A, B
Length: 409 amino acids
Theoretical weight: 44.61 KDa
Source organism: Zika virus
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A1B0XTC8 (Residues: 291-699; Coverage: 12%)
Sequence domains:
Structure domains:
Antibody heavy chain Chains: C, H
Molecule details ›
Chains: C, H
Length: 220 amino acids
Theoretical weight: 23.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins
Antibody light chain Chains: D, L
Molecule details ›
Chains: D, L
Length: 215 amino acids
Theoretical weight: 23.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2
Unit cell:
a: 128.668Å b: 97.504Å c: 165.753Å
α: 90° β: 91.52° γ: 90°
R-values:
R R work R free
0.233 0.231 0.277
Expression system: Escherichia coli