5gvs

X-ray diffraction
2.2Å resolution

Crystal structure of the DDX41 DEAD domain in an apo open form

Released:

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Probable ATP-dependent RNA helicase DDX41 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 231 amino acids
Theoretical weight: 25.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UJV9 (Residues: 169-399; Coverage: 37%)
Gene names: ABS, DDX41
Sequence domains: DEAD/DEAH box helicase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32XU
Unit cell:
a: 91.188Å b: 50.96Å c: 202.599Å
α: 90° β: 95.51° γ: 90°
R-values:
R R work R free
0.211 0.207 0.275
Expression system: Escherichia coli