5gpy

X-ray diffraction
2.1Å resolution

Crystal structure of the human TFIIE complex

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
General transcription factor IIE subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 220 amino acids
Theoretical weight: 25.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29083 (Residues: 1-217; Coverage: 49%)
Gene names: GTF2E1, TF2E1
Sequence domains:
Transcription initiation factor IIE subunit beta Chain: B
Molecule details ›
Chain: B
Length: 108 amino acids
Theoretical weight: 12.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29084 (Residues: 141-244; Coverage: 36%)
Gene names: GTF2E2, TF2E2
Sequence domains: TFA2 Winged helix domain 2

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P212121
Unit cell:
a: 51.52Å b: 69.2Å c: 116.53Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.198 0.237
Expression system: Escherichia coli