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The crystal structure of PECAM-1 IgL1-2 trans-homophilic dimer

X-ray diffraction
3.008Å resolution
PDB entry 5gni coloured by chain, front view.
PDB entry 5gni coloured by chain, side view.
PDB entry 5gni coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Platelet endothelial cell adhesion molecule
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Multimeric state: homo dimer
Accessible surface area: 19926.13 Å2
Buried surface area: 2173.17 Å2
Dissociation area: 1,086.59 Å2
Dissociation energy (ΔGdiss): -7.77 kcal/mol
Dissociation entropy (TΔSdiss): 13.13 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-147671

Macromolecules

Platelet endothelial cell adhesion molecule
Chains: A, B
Length: 213 amino acids
Theoretical weight: 24.55 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P16284 (Residues: 28-232; Coverage: 29%)
Gene name: PECAM1
InterPro:
Platelet endothelial cell adhesion molecule in PDB entry 5gni, assembly 1, front view.
Platelet endothelial cell adhesion molecule in PDB entry 5gni, assembly 1, side view.
Platelet endothelial cell adhesion molecule in PDB entry 5gni, assembly 1, top view.
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