5g6s

X-ray diffraction
2.35Å resolution

Imine reductase from Aspergillus oryzae in complex with NADP(H) and (R)-rasagiline

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NADPH-dependent reductive aminase Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 295 amino acids
Theoretical weight: 31.18 KDa
Source organism: Aspergillus oryzae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q2TW47 (Residues: 1-295; Coverage: 100%)
Gene name: AO090010000708
Sequence domains: NAD binding domain of 6-phosphogluconate dehydrogenase
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P1
Unit cell:
a: 79.822Å b: 80.255Å c: 123.895Å
α: 108.75° β: 108.78° γ: 90.05°
R-values:
R R work R free
0.206 0.204 0.229
Expression system: Escherichia coli BL21(DE3)