5fwv

X-ray diffraction
3.2Å resolution

Wnt modulator Kremen crystal form III at 3.2A

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kremen protein 1 Chain: A
Molecule details ›
Chain: A
Length: 406 amino acids
Theoretical weight: 44.55 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q96MU8 (Residues: 29-324, 326-373; Coverage: 76%)
  • Best match: Q96MU8-2 (Residues: 31-326, 328-375)
Gene names: KREMEN, KREMEN1, KRM1
Sequence domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P41212
Unit cell:
a: 67.844Å b: 67.844Å c: 198.193Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.195 0.265
Expression system: Homo sapiens