5fjw

X-ray diffraction
2.8Å resolution

Yeast delta-COP-I mu-homology domain complexed with Dsl1 WxWx(MSE) peptide

Released:
Source organism: Saccharomyces cerevisiae
Primary publication:
Structural basis for the binding of tryptophan-based motifs by δ-COP.
Proc Natl Acad Sci U S A 112 14242-7 (2015)
PMID: 26578768

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-155109 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Coatomer subunit delta Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 270 amino acids
Theoretical weight: 30.02 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P43621 (Residues: 288-546; Coverage: 47%)
Gene names: RET2, YFR051C
Sequence domains: Adaptor complexes medium subunit family
Protein transport protein DSL1 Chains: L, M, N, O, P, Q, R, S
Molecule details ›
Chains: L, M, N, O, P, Q, R, S
Length: 9 amino acids
Theoretical weight: 1.29 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided
UniProt:
  • Canonical: P53847 (Residues: 411-419; Coverage: 1%)
Gene names: DSL1, N0842, YNL258C

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P1
Unit cell:
a: 68.406Å b: 79.298Å c: 163.346Å
α: 79.71° β: 87.5° γ: 83.6°
R-values:
R R work R free
0.174 0.17 0.239
Expression systems:
  • Escherichia coli
  • Not provided