PDBe 5f7d

X-ray diffraction
2.3Å resolution

Structure of HLA-A2:01 with peptide G11N

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, A-2 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 273 amino acids
Theoretical weight: 31.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01892 (Residues: 26-298; Coverage: 80%)
Gene names: HLA-A, HLAA
Sequence domains: Immunoglobulin C1-set domain
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Peptide G11N Chain: C
Molecule details ›
Chain: C
Length: 10 amino acids
Theoretical weight: 1.01 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P21
Unit cell:
a: 56.268Å b: 79.509Å c: 58.281Å
α: 90° β: 115.96° γ: 90°
R-values:
R R work R free
0.212 0.209 0.257
Expression systems:
  • Escherichia coli
  • Not provided