Assemblies
Multimeric state:
hetero tetramer
Accessible surface area:
45602.24 Å2
Buried surface area:
12914.44 Å2
Dissociation area:
3,848.24
Å2
Dissociation energy (ΔGdiss):
27.98
kcal/mol
Dissociation entropy (TΔSdiss):
36.48
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-129992
Macromolecules
Chain: A
Length: 462 amino acids
Theoretical weight: 53.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Vacuolar protein sorting-associated protein 35
InterPro:
Length: 462 amino acids
Theoretical weight: 53.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q96QK1 (Residues: 14-470; Coverage: 57%)
Pfam: Vacuolar protein sorting-associated protein 35
InterPro:
Chain: B
Length: 321 amino acids
Theoretical weight: 37.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Vacuolar protein sorting-associated protein 26
InterPro:
CATH: Immunoglobulin-like
Length: 321 amino acids
Theoretical weight: 37.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O75436 (Residues: 1-321; Coverage: 98%)
Pfam: Vacuolar protein sorting-associated protein 26
InterPro:
CATH: Immunoglobulin-like
Chain: C
Length: 167 amino acids
Theoretical weight: 19.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: PX domain
InterPro:
CATH: Phox-like domain
Length: 167 amino acids
Theoretical weight: 19.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: O60493 (Residues: 1-162; Coverage: 100%)
Pfam: PX domain
InterPro:
CATH: Phox-like domain
Chain: D
Length: 18 amino acids
Theoretical weight: 2.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Length: 18 amino acids
Theoretical weight: 2.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P49281 (Residues: 549-560; Coverage: 2%)