X-ray diffraction
2.58Å resolution

Crystal structure of hnRNPA2B1 in complex with RNA


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Heterogeneous nuclear ribonucleoproteins A2/B1 Chain: A
Molecule details ›
Chain: A
Length: 184 amino acids
Theoretical weight: 21.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P22626 (Residues: 12-195; Coverage: 52%)
Gene names: HNRNPA2B1, HNRPA2B1
Sequence domains: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Structure domains: Alpha-Beta Plaits
RNA (5'-R(*AP*GP*GP*AP*CP*UP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 7 nucleotides
Theoretical weight: 2.26 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: C2
Unit cell:
a: 122.623Å b: 46.38Å c: 37.516Å
α: 90° β: 96.02° γ: 90°
R R work R free
0.194 0.192 0.236
Expression systems:
  • Escherichia coli
  • Not provided