› › Structure analysis

mACHE-anti TZ2PA5 complex from a 1:6 mixture of the syn/anti isomers

X-ray diffraction
2.7Å resolution
PDB entry 5eia coloured by chain, front view.
PDB entry 5eia coloured by chain, side view.
PDB entry 5eia coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Acetylcholinesterase
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 38243.99 Å2
Buried surface area: 3517.91 Å2
Dissociation area: 1,134.39 Å2
Dissociation energy (ΔGdiss): -4.67 kcal/mol
Dissociation entropy (TΔSdiss): 14.56 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-149441

Macromolecules

Acetylcholinesterase
Chains: A, B
Length: 543 amino acids
Theoretical weight: 59.76 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P21836 (Residues: 32-574; Coverage: 93%)
Gene name: Ache
Pfam: Carboxylesterase family
InterPro:
CATH: alpha/beta hydrolase
Acetylcholinesterase in PDB entry 5eia, assembly 1, front view.
Acetylcholinesterase in PDB entry 5eia, assembly 1, side view.
Acetylcholinesterase in PDB entry 5eia, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links