5ege

X-ray diffraction
2Å resolution

Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase

Released:

Function and Biology Details

Reaction catalysed:
sn-glycero-3-phosphocholine + H(2)O = glycerol + phosphocholine
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Glycerophosphocholine cholinephosphodiesterase ENPP6 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 429 amino acids
Theoretical weight: 49.6 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8BGN3 (Residues: 1-421; Coverage: 96%)
Gene name: Enpp6
Sequence domains: Type I phosphodiesterase / nucleotide pyrophosphatase
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUL
Carbohydrate polymer : NEW Components: NAG
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P1
Unit cell:
a: 64.29Å b: 78.24Å c: 103.64Å
α: 90.04° β: 89.98° γ: 114.61°
R-values:
R R work R free
0.169 0.167 0.206
Expression system: Homo sapiens