› 5ed7

X-ray diffraction
2.72Å resolution

Crystal Structure of HSV-1 UL21 C-terminal Domain

Released:
DOI: 10.2210/pdb5ed7/pdb
PDB entry 5ed7 coloured by chain, front view.
PDB entry 5ed7 coloured by chain, side view.
PDB entry 5ed7 coloured by chain, top view.
Source organism: Human alphaherpesvirus 1 strain 17
Primary publication:
Novel Structure and Unexpected RNA-Binding Ability of the C-Terminal Domain of Herpes Simplex Virus 1 Tegument Protein UL21.
Metrick CM, Heldwein EE
J Virol 90 5759-69 (2016)
PMID: 27053559

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145202 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tegument protein UL21 Chain: A
Molecule details ›
Chain: A
Length: 252 amino acids
Theoretical weight: 27.36 KDa
Source organism: Human alphaherpesvirus 1 strain 17
Expression system: Escherichia coli
UniProt:
  • Canonical: P10205 (Residues: 279-530; Coverage: 47%)
Gene name: UL21
Sequence domains: Herpesvirus UL21

Ligands and Environments

1 bound ligand:
Ligand CL 6 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P43212
Unit cell:
a: 54.273Å b: 54.273Å c: 180.757Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.218 0.234
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Alphaherpesvirus glycoprotein E: A review of its interactions with other proteins of the virus and its application in vaccinology.
Ning et al. (2022)
6 other articles

4 mentions without citation

Molecular Evolution of Herpes Simplex Virus 2 Complete Genomes: Comparison between Primary and Recurrent Infections.
Minaya et al. (2017)
3 more