5dvx

X-ray diffraction
1.6Å resolution

Crystal structure of the catalytic-domain of human carbonic anhydrase IX at 1.6 angstrom resolution

Released:

Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase 9 Chains: A, B
Molecule details ›
Chains: A, B
Length: 260 amino acids
Theoretical weight: 28.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16790 (Residues: 140-399; Coverage: 62%)
Gene names: CA9, G250, MN
Structure domains: Alpha carbonic anhydrase

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P212121
Unit cell:
a: 57.877Å b: 102.744Å c: 108.964Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.168 0.191
Expression system: Escherichia coli