X-ray diffraction
2.39Å resolution

Crystal structure of the Asn-bound guinea pig L-asparaginase 1 catalytic domain active site mutant K188M


Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Asparaginase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 588 amino acids
Theoretical weight: 63.39 KDa
Source organism: Cavia porcellus
Expression system: Escherichia coli
  • Canonical: H0W0T5 (Residues: 1-565; Coverage: 100%)
Gene name: ASPG
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: I222
Unit cell:
a: 123.91Å b: 154.79Å c: 157.31Å
α: 90° β: 90° γ: 90°
R R work R free
0.196 0.194 0.237
Expression system: Escherichia coli