PDBe 5dgo

X-ray diffraction
2.1Å resolution

Crystal structure of cell division cycle protein 45 (Cdc45)

Released:
Source organism: Homo sapiens

Function and Biology Details

Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cell division control protein 45 homolog Chain: A
Molecule details ›
Chain: A
Length: 555 amino acids
Theoretical weight: 64.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75419 (Residues: 1-566; Coverage: 98%)
Gene names: CDC45, CDC45L, CDC45L2, UNQ374/PRO710
Sequence domains: CDC45-like protein

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P3121
Unit cell:
a: 112.795Å b: 112.795Å c: 143.06Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.169 0.168 0.195
Expression system: Escherichia coli BL21(DE3)