5dea

X-ray diffraction
2.8Å resolution

Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, cesium bound form.

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Fragile X messenger ribonucleoprotein 1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 18 amino acids
Theoretical weight: 1.79 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q06787 (Residues: 527-544; Coverage: 3%)
Gene name: FMR1
sc1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 35 nucleotides
Theoretical weight: 11.46 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21212
Unit cell:
a: 56.57Å b: 129.87Å c: 36.79Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.202 0.226
Expression system: Not provided