PDBe 5dak

X-ray diffraction
2.11Å resolution

Crystal Structure of human Glutathione Transferase Pi complexed with a metalloid in the absence of Glutathione

Released:
Source organism: Homo sapiens
Entry authors: Parker LJ, Parker MW, Morton CJ

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Glutathione S-transferase P Chain: A
Molecule details ›
Chain: A
Length: 210 amino acids
Theoretical weight: 23.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P09211 (Residues: 1-210)
Gene names: FAEES3, GST3, GSTP1
Glutathione S-transferase P Chain: B
Molecule details ›
Chain: B
Length: 210 amino acids
Theoretical weight: 23.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Best match: P09211 (Residues: 1-210)
Gene names: FAEES3, GST3, GSTP1

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: C2
Unit cell:
a: 74.629Å b: 95.509Å c: 68.247Å
α: 90° β: 98.26° γ: 90°
R-values:
R R work R free
0.159 0.157 0.204
Expression system: Escherichia coli