Assemblies
Assembly Name:
Epidermal growth factor receptor
Multimeric state:
homo dimer
Accessible surface area:
25850.87 Å2
Buried surface area:
5185.07 Å2
Dissociation area:
1,574.62
Å2
Dissociation energy (ΔGdiss):
16.53
kcal/mol
Dissociation entropy (TΔSdiss):
13.7
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-132701
Macromolecules
Chains: A, B
Length: 331 amino acids
Theoretical weight: 37.72 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
Length: 331 amino acids
Theoretical weight: 37.72 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P00533 (Residues: 695-1022; Coverage: 28%)
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
- Protein kinase-like domain superfamily
- Protein kinase domain
- Tyrosine-protein kinase, catalytic domain
- Serine-threonine/tyrosine-protein kinase, catalytic domain
- Protein kinase, ATP binding site
- Tyrosine-protein kinase, active site
