5cmd

X-ray diffraction
3.09Å resolution

Oligomer crystal structure of CC chemokine 5 (CCL5)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 5 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 65 amino acids
Theoretical weight: 7.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13501 (Residues: 27-91; Coverage: 96%)
Gene names: CCL5, D17S136E, SCYA5
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P62
Unit cell:
a: 124.72Å b: 124.72Å c: 127.05Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.217 0.213 0.258
Expression system: Escherichia coli