PDBe 5ckr

X-ray diffraction
2.95Å resolution

Crystal Structure of MraY in complex with Muraymycin D2

Released:

Function and Biology Details

Reaction catalysed:
UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phospho-N-acetylmuramoyl-pentapeptide-transferase Chain: A
Molecule details ›
Chain: A
Length: 365 amino acids
Theoretical weight: 40.95 KDa
Source organism: Aquifex aeolicus VF5
Expression system: Escherichia coli
UniProt:
  • Canonical: O66465 (Residues: 1-359; Coverage: 100%)
Gene names: aq_053, mraY
Sequence domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: C2221
Unit cell:
a: 94.48Å b: 102.05Å c: 135.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.247 0.261
Expression system: Escherichia coli