Function and Biology Details
Reaction catalysed:
ATP-dependent breakage, passage and rejoining of double-stranded DNA
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- DNA topoisomerase, type IIA, domain A
- TOPRIM domain
- DNA topoisomerase, type IIA-like domain superfamily
- DNA gyrase B subunit, C-terminal
- DNA topoisomerase, type IIA, conserved site
- DNA gyrase subunit B, TOPRIM domain
- DNA topoisomerase, type IIA, subunit B, C-terminal
- DNA topoisomerase, type IIA
2 more domains
Structure analysis Details
Assembly composition:
hetero octamer (preferred)
Assembly name:
DNA gyrase and DNA (preferred)
PDBe Complex ID:
PDB-CPX-118475 (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (4 distinct):
DNA gyrase subunit A
Molecule details ›
Chains: A, C
Length: 483 amino acids
Theoretical weight: 54.74 KDa
Source organism: Staphylococcus aureus subsp. aureus N315
Expression system: Escherichia coli
UniProt:
Sequence domains: DNA gyrase/topoisomerase IV, subunit A
Length: 483 amino acids
Theoretical weight: 54.74 KDa
Source organism: Staphylococcus aureus subsp. aureus N315
Expression system: Escherichia coli
UniProt:
- Canonical:
Q99XG5 (Residues: 9-491; Coverage: 54%)
Sequence domains: DNA gyrase/topoisomerase IV, subunit A
DNA gyrase subunit B
Molecule details ›
Chains: B, D
Length: 190 amino acids
Theoretical weight: 21.35 KDa
Source organism: Staphylococcus aureus subsp. aureus N315
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 190 amino acids
Theoretical weight: 21.35 KDa
Source organism: Staphylococcus aureus subsp. aureus N315
Expression system: Escherichia coli
UniProt:
- Canonical: P66937 (Residues: 417-543, 580-640; Coverage: 29%)
Sequence domains:
