Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146312 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mothers against decapentaplegic homolog 4
Molecule details ›
Chains: A, C, E
Length: 258 amino acids
Theoretical weight: 28.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4
Length: 258 amino acids
Theoretical weight: 28.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q13485 (Residues: 314-549; Coverage: 43%)
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4
Ski-like protein
Molecule details ›
Chains: B, D, F
Length: 127 amino acids
Theoretical weight: 14.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: c-SKI Smad4 binding domain
Structure domains: SAND domain-like
Length: 127 amino acids
Theoretical weight: 14.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P12757 (Residues: 238-356; Coverage: 17%)
Sequence domains: c-SKI Smad4 binding domain
Structure domains: SAND domain-like
