› 5bu2

X-ray diffraction
2.11Å resolution

Structure of the C-terminal domain of lpg1496 from Legionella pneumophila in complex with nucleotide

Released:
DOI: 10.2210/pdb5bu2/pdb
PDB entry 5bu2 coloured by chain, front view.
PDB entry 5bu2 coloured by chain, side view.
PDB entry 5bu2 coloured by chain, top view.
Source organism: Legionella pneumophila subsp. pneumophila ATCC 43290
Primary publication:
Structure of the Legionella Effector, lpg1496, Suggests a Role in Nucleotide Metabolism.
Wong K, Kozlov G, Zhang Y, Gehring K
J Biol Chem 290 24727-37 (2015)
PMID: 26294765

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165471 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
lpg1496 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 454 amino acids
Theoretical weight: 51.23 KDa
Source organism: Legionella pneumophila subsp. pneumophila ATCC 43290
Expression system: Escherichia coli BL21

Ligands and Environments

3 bound ligands:
Ligand ADP 4 x ADP
Ligand AMP 1 x AMP
Ligand RIB 1 x RIB
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P1
Unit cell:
a: 56.867Å b: 69.707Å c: 77.027Å
α: 89.87° β: 72.3° γ: 70.31°
R-values:
R R work R free
0.231 0.229 0.273
Expression system: Escherichia coli BL21

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Citations

6 citation in other articles

A Single Legionella Effector Catalyzes a Multistep Ubiquitination Pathway to Rearrange Tubular Endoplasmic Reticulum for Replication.
Kotewicz et al. (2017)
5 more

2 mentions without citation

Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination.
Kalayil et al. (2018)
1 more