› 5bpv

X-ray diffraction
1.95Å resolution

Crystal Structure of Zaire ebolavirus VP35 RNA binding domain mutant I278A

Released:
DOI: 10.2210/pdb5bpv/pdb
PDB entry 5bpv coloured by chain, front view.
PDB entry 5bpv coloured by chain, side view.
PDB entry 5bpv coloured by chain, top view.
Source organism: Zaire ebolavirus
Entry authors: Fadda V, Cannas V, Zinzula L, Distinto S, Daino GL, Bianco G, Corona A, Esposito F, Alcaro S, Maccioni E, Tramontano E, Taylor GL

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170140 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polymerase cofactor VP35 Chains: A, B
Molecule details ›
Chains: A, B
Length: 124 amino acids
Theoretical weight: 13.66 KDa
Source organism: Zaire ebolavirus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q05127 (Residues: 217-340; Coverage: 37%)
Gene name: VP35
Sequence domains: Filoviridae VP35
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 51.75Å b: 65.66Å c: 72.02Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.18 0.218
Expression system: Escherichia coli

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