5bpq

X-ray diffraction
2.4Å resolution

Crystal structure of the cysteine-rich domain of human Frizzled 4 - Crystal Form II

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Frizzled-4 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 149 amino acids
Theoretical weight: 16.71 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9ULV1 (Residues: 42-179; Coverage: 28%)
Gene name: FZD4
Sequence domains: Fz domain
Structure domains: Frizzled cysteine-rich domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P61
Unit cell:
a: 76.075Å b: 76.075Å c: 204.47Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.206 0.204 0.243
Expression system: Homo sapiens