Function and Biology Details
Reactions catalysed:
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- EF-hand domain
- Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
- EF-Hand 1, calcium-binding site
- FKBP-type peptidyl-prolyl cis-trans isomerase domain
- Metallo-dependent phosphatase-like
- Peptidyl-prolyl cis-trans isomerase domain superfamily
- Calcineurin B protein
- EF-hand domain pair
3 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-101158 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Serine/threonine-protein phosphatase
Molecule details ›
Chain: A
Length: 390 amino acids
Theoretical weight: 45.1 KDa
Source organism: Coccidioides immitis RS
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Calcineurin-like phosphoesterase
Structure domains: Purple Acid Phosphatase; chain A, domain 2
Length: 390 amino acids
Theoretical weight: 45.1 KDa
Source organism: Coccidioides immitis RS
Expression system: Trichoplusia ni
UniProt:
- Canonical:
J3K8M7 (Residues: 27-395; Coverage: 67%)
Sequence domains: Calcineurin-like phosphoesterase
Structure domains: Purple Acid Phosphatase; chain A, domain 2
Calcineurin subunit B
Molecule details ›
Chain: B
Length: 171 amino acids
Theoretical weight: 19.5 KDa
Source organism: Coccidioides immitis RS
Expression system: Trichoplusia ni
UniProt:
Sequence domains: EF-hand domain pair
Structure domains: EF-hand
Length: 171 amino acids
Theoretical weight: 19.5 KDa
Source organism: Coccidioides immitis RS
Expression system: Trichoplusia ni
UniProt:
- Canonical: A0A0D8JSK0 (Residues: 22-191; Coverage: 89%)
Sequence domains: EF-hand domain pair
Structure domains: EF-hand
peptidylprolyl isomerase
Molecule details ›
Chain: C
Length: 130 amino acids
Theoretical weight: 14.46 KDa
Source organism: Coccidioides immitis RS
Expression system: Trichoplusia ni
UniProt:
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase
Structure domains: Chitinase A; domain 3
Length: 130 amino acids
Theoretical weight: 14.46 KDa
Source organism: Coccidioides immitis RS
Expression system: Trichoplusia ni
UniProt:
- Canonical: J3K5Z5 (Residues: 2-120; Coverage: 99%)
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase
Structure domains: Chitinase A; domain 3
