Function and Biology

Crystal structure of the HypAB-Ni complex

Source organism: Thermococcus kodakarensis KOD1
Biochemical function: metal ion binding
Biological process: mitochondrial respiratory chain complex I assembly
Cellular component: cytosol

Sequence families

Pfam Protein families (Pfam)
PF10609
Domain description: NUBPL iron-transfer P-loop NTPase
Occurring in:
  1. Iron-sulfur cluster carrier protein
The deposited structure of PDB entry 5aun contains 1 copy of Pfam domain PF10609 (NUBPL iron-transfer P-loop NTPase) in Iron-sulfur cluster carrier protein. Showing 1 copy in chain B.

PF01155
Domain description: Hydrogenase/urease nickel incorporation, metallochaperone, hypA
Occurring in:
  1. Hydrogenase maturation factor HypA
The deposited structure of PDB entry 5aun contains 1 copy of Pfam domain PF01155 (Hydrogenase/urease nickel incorporation, metallochaperone, hypA) in Hydrogenase maturation factor HypA. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR019591
Domain description: Mrp/NBP35 ATP-binding protein
Occurring in:
  1. Iron-sulfur cluster carrier protein
IPR000688
Domain description: Hydrogenase maturation factor HypA/HybF
Occurring in:
  1. Hydrogenase maturation factor HypA
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Iron-sulfur cluster carrier protein
IPR033756
Domain description: Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35
Occurring in:
  1. Iron-sulfur cluster carrier protein
IPR044304
Domain description: Iron-sulfur protein NUBPL-like
Occurring in:
  1. Iron-sulfur cluster carrier protein
IPR020538
Domain description: Hydrogenase nickel incorporation protein HypA/HybF, conserved site
Occurring in:
  1. Hydrogenase maturation factor HypA

Structure domains

CATH CATH domains
3.30.2320.50
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: hypothetical protein PF0899 fold
Homology: hypothetical protein PF0899 fold
Occurring in:
  1. Hydrogenase maturation factor HypA
The deposited structure of PDB entry 5aun contains 1 copy of CATH domain 3.30.2320.50 (hypothetical protein PF0899 fold) in Hydrogenase maturation factor HypA. Showing 1 copy in chain A.
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Iron-sulfur cluster carrier protein
The deposited structure of PDB entry 5aun contains 1 copy of CATH domain 3.40.50.300 (Rossmann fold) in Iron-sulfur cluster carrier protein. Showing 1 copy in chain B.