PDBe 5afh

X-ray diffraction
2.4Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acetylcholine-binding protein; Neuronal acetylcholine receptor subunit alpha-7 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 205 amino acids
Theoretical weight: 23.7 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P58154 (Residues: 36-46, 67-72, 92-122, 130-130, 135-155, 163-168, 187-191, 195-198, 220-224; Coverage: 43%)
  • Canonical: P36544 (Residues: 23-39, 52-71, 78-98, 131-137, 139-142, 165-171, 178-192, 198-200, 205-225; Coverage: 24%)
  • nullnull
Gene names: CHRNA7, NACHRA7
Structure domains: Neurotransmitter-gated ion-channel ligand-binding domain

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P212121
Unit cell:
a: 85.52Å b: 112.504Å c: 143.109Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.168 0.227
Expression system: Spodoptera frugiperda