X-ray diffraction
2.28Å resolution

Open and closed conformations and protonation states of Candida antarctica Lipase B: Xenon complex


Function and Biology Details

Reaction catalysed:
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Lipase B Chains: A, B
Molecule details ›
Chains: A, B
Length: 317 amino acids
Theoretical weight: 33.04 KDa
Source organism: Moesziomyces antarcticus
Expression system: Aspergillus oryzae
  • Canonical: P41365 (Residues: 26-342; Coverage: 98%)
Structure domains: alpha/beta hydrolase

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
Spacegroup: P1
Unit cell:
a: 39.656Å b: 48.89Å c: 71.68Å
α: 87.8° β: 98.07° γ: 108.17°
R R work R free
0.142 0.139 0.195
Expression system: Aspergillus oryzae