5a1k

X-ray diffraction
2.9Å resolution

Crystal structure of calcium-free human adseverin domains A1-A3

Released:
Source organism: Homo sapiens
Entry authors: Chumnarnsilpa S, Robinson RC, Grimes JM, Leyrat C

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Scinderin Chains: A, B
Molecule details ›
Chains: A, B
Length: 344 amino acids
Theoretical weight: 38.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y6U3 (Residues: 6-349; Coverage: 48%)
Gene names: KIAA1905, SCIN
Sequence domains: Gelsolin repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 135.41Å b: 65.25Å c: 105.19Å
α: 90° β: 118.27° γ: 90°
R-values:
R R work R free
0.24 0.24 0.248
Expression system: Escherichia coli BL21(DE3)