PDBe 5ypu

X-ray diffraction
2Å resolution

Crystal structure of an actin monomer in complex with the nucleator Cordon-Bleu MET72NLE WH2-motif peptide


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Actin, alpha skeletal muscle Chains: A, C
Molecule details ›
Chains: A, C
Length: 368 amino acids
Theoretical weight: 40.99 KDa
Source organism: Oryctolagus cuniculus
  • Canonical: P68135 (Residues: 7-374; Coverage: 98%)
Gene names: ACTA, ACTA1
Protein cordon-bleu Chains: B, D
Molecule details ›
Chains: B, D
Length: 22 amino acids
Theoretical weight: 2.39 KDa
Source organism: Mus musculus
Expression system: Not provided
  • Canonical: Q5NBX1 (Residues: 1184-1204; Coverage: 2%)
Gene names: Cobl, Kiaa0633

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: C2
Unit cell:
a: 174.861Å b: 40.832Å c: 109Å
α: 90° β: 101.76° γ: 90°
R R work R free
0.195 0.193 0.24
Expression system: Not provided