5xv7

X-ray diffraction
2.32Å resolution

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SRSF protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 372 amino acids
Theoretical weight: 42.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: Q96SB4 (Residues: 67-655; Coverage: 57%)
Gene name: SRPK1
Sequence domains: Protein kinase domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: P6522
Unit cell:
a: 74.767Å b: 74.767Å c: 310.687Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.213 0.212 0.238
Expression system: Escherichia coli K-12