PDBe 5xjm

X-ray diffraction
3.2Å resolution

Complex structure of angiotensin II type 2 receptor with Fab

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Soluble cytochrome b562; Type-2 angiotensin II receptor Chain: A
Molecule details ›
Chain: A
Length: 422 amino acids
Theoretical weight: 48.06 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P0ABE7 (Residues: 23-128; Coverage: 100%)
  • Canonical: P50052 (Residues: 35-242, 246-346; Coverage: 85%)
  • nullnull
Gene names: AGTR2, cybC
Sequence domains:
FabH Chain: H
Molecule details ›
Chain: H
Length: 220 amino acids
Theoretical weight: 23.37 KDa
Source organism: Mus musculus
FabL Chain: L
Molecule details ›
Chain: L
Length: 212 amino acids
Theoretical weight: 23.26 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Angiotensin-4 Chain: B
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 970 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01019 (Residues: 35-40; Coverage: 1%)
Gene names: AGT, SERPINA8

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32XU
Spacegroup: P21212
Unit cell:
a: 465.39Å b: 48.65Å c: 55.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.226 0.275
Expression systems:
  • Spodoptera frugiperda
  • Mus musculus
  • Not provided