PDBe 5wp3

X-ray diffraction
2.55Å resolution

Crystal Structure of EED in complex with EB22

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Polycomb protein EED Chain: A
Molecule details ›
Chain: A
Length: 368 amino acids
Theoretical weight: 42.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75530 (Residues: 75-441; Coverage: 83%)
Gene name: EED
Sequence domains: WD domain, G-beta repeat
EB22 Chain: B
Molecule details ›
Chain: B
Length: 121 amino acids
Theoretical weight: 13.99 KDa
Source organism: synthetic construct
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21212
Unit cell:
a: 57.07Å b: 134.29Å c: 61.94Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.204 0.244
Expression system: Escherichia coli BL21(DE3)